Microwave assisted synthesis of substituted (Z)-2-{[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol- 4-yl]methylene}benzofuran-3(2H)-ones and their antimicrobial activity
- 作者: Ashok D.1, Ziauddin M.1,2, Lakshmi B.1, Sarasija M.1
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隶属关系:
- Green and Medical Chemistry Laboratory, Department of Chemistry
- Department of Pharmaceutical Sciences, University College of Technology
- 期: 卷 86, 编号 7 (2016)
- 页面: 1753-1757
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215845
- DOI: https://doi.org/10.1134/S1070363216070355
- ID: 215845
如何引用文章
详细
Aurones, pyrazole and thiophene scaffolds are known for their potential antimicrobial activity. Herein, we have synthesized hybrid compounds containing three substituted (Z)-2-{[1-phenyl-3-(thiophen-2-yl)- 1H-pyrazol-4-yl]methylene}benzofuran-3(2H)-ones that had been produced from substituted (E)-1-(2-hydroxyphenyl)- 3-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]prop-2-en-1-ones in high yields. All synthesized compounds were tested in vitro for their antimicrobial activity. Several of those demonstrated promising activity against some fungal and bacterial strains.
作者简介
D. Ashok
Green and Medical Chemistry Laboratory, Department of Chemistry
编辑信件的主要联系方式.
Email: ashokdou@gmail.com
印度, Hyderabad, 500007
M. Ziauddin
Green and Medical Chemistry Laboratory, Department of Chemistry; Department of Pharmaceutical Sciences, University College of Technology
Email: ashokdou@gmail.com
印度, Hyderabad, 500007; Hyderabad, 500007
B. Lakshmi
Green and Medical Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
印度, Hyderabad, 500007
M. Sarasija
Green and Medical Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
印度, Hyderabad, 500007
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