Synthesis of some novel S-alkylated and S-glycosylated hydantoin derivatives containing pyrene moiety


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详细

3-Aryl-5-[(Z)-pyrenylmethylene]-2-alkylthiohydantoins and 3-Aryl-5-[(Z)-pyrenylmethylene]-2-(D-glycosyl)-2-thiohydantoins functionalized with different aromatic and glycoside substituents have been synthesized by the reaction of (Z)-3-(4-methoxyphenyl)-5-[(pyren-8-yl)methylene]-2-thiohydantoin with alkyl halides, cyclic and acyclic nucleosides via various routes with moderate to good yields and characterized by 1H, 13C NMR and mass spectra and elemental analysis

作者简介

N. Khalifa

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division

编辑信件的主要联系方式.
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Cairo, Dokki, 12622

E. Nossier

Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)

Email: nagykhalifa@hotmail.com
埃及, Cairo

M. Al-Omar

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy

Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451

A. Amr

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Applied Organic Chemistry Department

Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Cairo, Dokki, 12622


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