Synthesis of some novel S-alkylated and S-glycosylated hydantoin derivatives containing pyrene moiety
- Авторы: Khalifa N.1,2, Nossier E.3, Al-Omar M.1, Amr A.1,4
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Учреждения:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- Applied Organic Chemistry Department
- Выпуск: Том 86, № 4 (2016)
- Страницы: 919-923
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/214738
- DOI: https://doi.org/10.1134/S1070363216040277
- ID: 214738
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Аннотация
3-Aryl-5-[(Z)-pyrenylmethylene]-2-alkylthiohydantoins and 3-Aryl-5-[(Z)-pyrenylmethylene]-2-(D-glycosyl)-2-thiohydantoins functionalized with different aromatic and glycoside substituents have been synthesized by the reaction of (Z)-3-(4-methoxyphenyl)-5-[(pyren-8-yl)methylene]-2-thiohydantoin with alkyl halides, cyclic and acyclic nucleosides via various routes with moderate to good yields and characterized by 1H, 13C NMR and mass spectra and elemental analysis
Об авторах
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Автор, ответственный за переписку.
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451; Cairo, Dokki, 12622
E. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
Египет, Cairo
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451
A. Amr
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Applied Organic Chemistry Department
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451; Cairo, Dokki, 12622
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