Design and Synthesis of Novel β-Carboline Linked Amide Derivatives as Anticancer Agents
- Авторы: Ravinaik B.1, Ramachandran D.1, Basaveswara Rao M.2
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Учреждения:
- Department of Chemistry
- Department of Chemistry, Dr. MRAR. PG Centre
- Выпуск: Том 89, № 3 (2019)
- Страницы: 511-516
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222803
- DOI: https://doi.org/10.1134/S1070363219030241
- ID: 222803
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Аннотация
A novel series of β-carboline linked amide derivatives is synthesized. The compounds are screened for their anticancer activity against MCF-7 (breast), A549 (lung), Colo-205 (colon), and A2780 (ovarian) cancer cell lines. The compounds 12b and 12h demonstrate the activity higher than the standard drug etoposide.
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Об авторах
B. Ravinaik
Department of Chemistry
Email: dittakavirc@gmail.com
Индия, Machilipatnam, Andhra Pradesh, 521001
D. Ramachandran
Department of Chemistry
Автор, ответственный за переписку.
Email: dittakavirc@gmail.com
Индия, Nagarjuna Nagar, Andhra Pradesh, 522510
M. Basaveswara Rao
Department of Chemistry, Dr. MRAR. PG Centre
Email: dittakavirc@gmail.com
Индия, Nuzvid, Andhra Pradesh, 521201