Email this article Design and Synthesis of Novel β-Carboline Linked Amide Derivatives as Anticancer Agents
- Authors: Ravinaik B.1, Ramachandran D.1, Basaveswara Rao M.V.2
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Affiliations:
- Department of Chemistry
- Department of Chemistry, Dr. MRAR. PG Centre
- Issue: Vol 89, No 3 (2019)
- Pages: 511-516
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222803
- DOI: https://doi.org/10.1134/S1070363219030241
- ID: 222803
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Abstract
A novel series of β-carboline linked amide derivatives is synthesized. The compounds are screened for their anticancer activity against MCF-7 (breast), A549 (lung), Colo-205 (colon), and A2780 (ovarian) cancer cell lines. The compounds 12b and 12h demonstrate the activity higher than the standard drug etoposide.
About the authors
B. Ravinaik
Department of Chemistry
Email: dittakavirc@gmail.com
India, Machilipatnam, Andhra Pradesh, 521001
D. Ramachandran
Department of Chemistry
Author for correspondence.
Email: dittakavirc@gmail.com
India, Nagarjuna Nagar, Andhra Pradesh, 522510
M. V. Basaveswara Rao
Department of Chemistry, Dr. MRAR. PG Centre
Email: dittakavirc@gmail.com
India, Nuzvid, Andhra Pradesh, 521201
