Synthesis and Antitubercular, Antimicrobial, and Hemolytic Activity of Methyl D-Glucopyranuronate and Its Simplest Derivatives
- Авторы: Belenok M.1, Andreeva O.1, Garifullin B.1, Strobykina A.1, Kravchenko M.2, Voloshina A.1, Kataev V.1
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Учреждения:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Ural Research Institute of Phthisiopulmonology
- Выпуск: Том 87, № 12 (2017)
- Страницы: 2816-2825
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221690
- DOI: https://doi.org/10.1134/S1070363217120106
- ID: 221690
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Аннотация
Methyl glucuronate and some of its simplest derivatives have been synthesized, and their antitubercular, antimicrobial, and hemolytic activities have been studied. The simplest derivatives of glucuronic acid have been shown for the first time to exhibit a high antitubercular activity which is comparable with the activity of isoniazid.
Об авторах
M. Belenok
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Россия, ul. Arbuzova 8, Kazan, Tatarstan, 420088
O. Andreeva
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Россия, ul. Arbuzova 8, Kazan, Tatarstan, 420088
B. Garifullin
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Россия, ul. Arbuzova 8, Kazan, Tatarstan, 420088
A. Strobykina
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Россия, ul. Arbuzova 8, Kazan, Tatarstan, 420088
M. Kravchenko
Ural Research Institute of Phthisiopulmonology
Email: kataev@iopc.ru
Россия, ul. 22 Parts”ezda 50, Yekaterinburg, 620039
A. Voloshina
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Россия, ul. Arbuzova 8, Kazan, Tatarstan, 420088
V. Kataev
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Автор, ответственный за переписку.
Email: kataev@iopc.ru
Россия, ul. Arbuzova 8, Kazan, Tatarstan, 420088
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