Synthesis, characterization, and antimicrobial activity of novel substituted 2H-chromenyl acrylates
- Авторы: Subhashini N.1, Ravi M.1, Cherupally D.2, China Raju B.2, Reddy E.2, Bee H.3
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Учреждения:
- Department of Pharmacy, University College of Technology
- Natural Products Chemistry Division
- Department of Microbiology, University College of Science
- Выпуск: Том 86, № 12 (2016)
- Страницы: 2900-2905
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/217365
- DOI: https://doi.org/10.1134/S1070363216120586
- ID: 217365
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Аннотация
The present study deals with conventional Witting olefination of 2H-chromene-3-carbaldehydes with stabilized ylide in the presence of dichloromethane to afford (2E)-ethyl-3-(4-chloro-2H-chromen-3-yl) acrylate derivatives. All the products were found to have E-geometry at C=C bond. The synthesized compounds were characterized by spectral data such as IR, 1H NMR and MS. Compounds were screened for antimicrobial activity against strains of gram positive, gram negative bacterial and fungal strains. All compounds showed good antibacterial and antifungal activity.
Об авторах
N. Subhashini
Department of Pharmacy, University College of Technology
Автор, ответственный за переписку.
Email: njsubhashini@yahoo.co.in
Индия, Hyderabad, 500007
M. Ravi
Department of Pharmacy, University College of Technology
Email: njsubhashini@yahoo.co.in
Индия, Hyderabad, 500007
D. Cherupally
Natural Products Chemistry Division
Email: njsubhashini@yahoo.co.in
Индия, Tarnaka
B. China Raju
Natural Products Chemistry Division
Email: njsubhashini@yahoo.co.in
Индия, Tarnaka
E. Reddy
Natural Products Chemistry Division
Email: njsubhashini@yahoo.co.in
Индия, Tarnaka
H. Bee
Department of Microbiology, University College of Science
Email: njsubhashini@yahoo.co.in
Индия, Hyderabad, 500007
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