Synthesis, characterization, and antimicrobial activity of novel substituted 2H-chromenyl acrylates
- Авторлар: Subhashini N.1, Ravi M.1, Cherupally D.2, China Raju B.2, Reddy E.2, Bee H.3
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Мекемелер:
- Department of Pharmacy, University College of Technology
- Natural Products Chemistry Division
- Department of Microbiology, University College of Science
- Шығарылым: Том 86, № 12 (2016)
- Беттер: 2900-2905
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/217365
- DOI: https://doi.org/10.1134/S1070363216120586
- ID: 217365
Дәйексөз келтіру
Аннотация
The present study deals with conventional Witting olefination of 2H-chromene-3-carbaldehydes with stabilized ylide in the presence of dichloromethane to afford (2E)-ethyl-3-(4-chloro-2H-chromen-3-yl) acrylate derivatives. All the products were found to have E-geometry at C=C bond. The synthesized compounds were characterized by spectral data such as IR, 1H NMR and MS. Compounds were screened for antimicrobial activity against strains of gram positive, gram negative bacterial and fungal strains. All compounds showed good antibacterial and antifungal activity.
Авторлар туралы
N. Subhashini
Department of Pharmacy, University College of Technology
Хат алмасуға жауапты Автор.
Email: njsubhashini@yahoo.co.in
Үндістан, Hyderabad, 500007
M. Ravi
Department of Pharmacy, University College of Technology
Email: njsubhashini@yahoo.co.in
Үндістан, Hyderabad, 500007
D. Cherupally
Natural Products Chemistry Division
Email: njsubhashini@yahoo.co.in
Үндістан, Tarnaka
B. China Raju
Natural Products Chemistry Division
Email: njsubhashini@yahoo.co.in
Үндістан, Tarnaka
E. Reddy
Natural Products Chemistry Division
Email: njsubhashini@yahoo.co.in
Үндістан, Tarnaka
H. Bee
Department of Microbiology, University College of Science
Email: njsubhashini@yahoo.co.in
Үндістан, Hyderabad, 500007