Enviar artigo por via de e-mail Synthesis, Structure, and Biological Activity of 4-R-4-Oxo-2-[2-(phenylamino)benzoyl]hydrazinylidene-N-hetarylbutanamides
- Autores: Kizimova I.1, Igidov N.1, Dmitriev M.2, Chashchina S.1,2, Makhmudov R.2,3, Siutkina A.1
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Afiliações:
- Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
- Perm State National Research University
- Federal Research Center for Medical and Preventive Health Risk Management Technologies
- Edição: Volume 89, Nº 12 (2019)
- Páginas: 2345-2352
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223186
- DOI: https://doi.org/10.1134/S107036321912003X
- ID: 223186
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Resumo
Decyclization of N′-[5-R-2-oxofuran-3(2H)-ylidene]-2-(phenylamino)benzohydrazides under the action of heterocyclic amines leads to the formation of N-hetaryl-4-R-4-oxo-2-[2-(phenylamino)benzoyl]hydrazinylidenebutanamides. Antinociceptive and anti-inflammatory activity of the obtained compounds was studied.
Sobre autores
I. Kizimova
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: icekingakiratotsuka@gmail.com
Rússia, Perm, 614990
N. Igidov
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: icekingakiratotsuka@gmail.com
Rússia, Perm, 614990
M. Dmitriev
Perm State National Research University
Email: icekingakiratotsuka@gmail.com
Rússia, Perm, 614068
S. Chashchina
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation; Perm State National Research University
Email: icekingakiratotsuka@gmail.com
Rússia, Perm, 614990; Perm, 614068
R. Makhmudov
Perm State National Research University; Federal Research Center for Medical and Preventive Health Risk Management Technologies
Email: icekingakiratotsuka@gmail.com
Rússia, Perm, 614068; Perm, 614045
A. Siutkina
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: icekingakiratotsuka@gmail.com
Rússia, Perm, 614990
