Enviar artigo por via de e-mail Synthesis, Structure, and Biological Activity of Cinnamoyl-Containing Cytisine and Anabasine Alkaloids Derivatives
- Autores: Nurkenov O.1, Nurmaganbetov Z.1,2, Seilkhanov T.3, Fazylov S.1, Satpayeva Z.1, Turdybekov K.4, Talipov S.5, Seydakhmetova R.6
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Afiliações:
- Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan
- Karaganda State Medical University
- Sh. Ualikhanov Kokshetau State University
- E.A. Buketov Karaganda State University
- A.S. Sadykov Institute of Bioorganic Chemistry
- International Research and Production Holding “Phytochemistry”
- Edição: Volume 89, Nº 10 (2019)
- Páginas: 2044-2051
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223112
- DOI: https://doi.org/10.1134/S1070363219100098
- ID: 223112
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Resumo
The reactions of the cytisine and anabasine alkaloids with cinnamic acid chloride have been studied, and hydrazinolysis of the resulting N-cinnamoylcytisine and N-cinnamoylanabazine has been carried out. The reaction of cinnamoyl isothiocyanate with alkaloids has afforded the corresponding thiourea derivatives. Antimicrobial and cytotoxic activity of cinnamoyl-containing derivatives of these alkaloids has been evaluated.
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Sobre autores
O. Nurkenov
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan
Autor responsável pela correspondência
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008
Zh. Nurmaganbetov
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan; Karaganda State Medical University
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008; Karaganda
T. Seilkhanov
Sh. Ualikhanov Kokshetau State University
Email: nurkenov_oral@mail.ru
Cazaquistão, Kokshetau
S. Fazylov
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008
Zh. Satpayeva
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan
Email: nurkenov_oral@mail.ru
Cazaquistão, ul. Alikhanova 1, Karaganda, 100008
K. Turdybekov
E.A. Buketov Karaganda State University
Email: nurkenov_oral@mail.ru
Cazaquistão, Karaganda
S. Talipov
A.S. Sadykov Institute of Bioorganic Chemistry
Email: nurkenov_oral@mail.ru
Uzbequistão, Tashkent
R. Seydakhmetova
International Research and Production Holding “Phytochemistry”
Email: nurkenov_oral@mail.ru
Cazaquistão, Karaganda
