Phosphorylation of 1,4:3,6-Dianhydro-d-sorbitol

Resumo

Regioselective mono- and diphosphorylation of 1,4:3,6-dianhydro-d-sorbitol containing two hydroxyl groups differing in steric availability has been studied. The nature of the amine acting as activator and acceptor of hydrogen chloride have had significant impact on the direction of phosphorylation and the structure of the resulting products.