Comparative Study of Redox Reactions of Aqua- and Thiocyanatocobalamin

Resumo

The interaction of aqua- and thiocyanatocobalamin with sodium hydroxymethanesulfinate in neutral aqueous solution has been studied, and the kinetic as well as activation parameters of the reactions have been determined. The reduction of the aqua complex is faster in comparison with the thiocyanato one. In contrast to the earlier studied reaction of hydroxymethanesulfinate with cyanocobalamin, reduction of aquaand thiocycnatocobalamins occurs via the associative mechanism.