Synthesis, Characterization, and Biological Activity of Organotin(IV) Complexes with Schiff Bases
- Autores: Nazneen S.1, Ali S.1, Shahzadi S.1, Shujah S.1
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Afiliações:
- Department of Chemistry
- Edição: Volume 87, Nº 12 (2017)
- Páginas: 2970-2978
- Seção: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221794
- DOI: https://doi.org/10.1134/S1070363217120404
- ID: 221794
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Resumo
The synthesized Schiff base ligands H2L1, N,N'-bis(2-hydroxybenzylidene)1,2-diaminobenzene, and H2L2, N,N'-bis(2-hydroxybenzylidene)hydrazine, reacted with Alk2SnCl2 to give organotin(IV) complexes 1–10. The products were characterized by elemental analysis, FTIR, 1H and 13C NMR, and mass spectrometry. All organotin(IV) derivatives with [O,N,O] donor ligands retained their 5-coordinated geometry in solid state and solutions. Most of synthesized complexes exhibited significant antibacterial activity. Cytotoxicity was also tested by using the brine shrimp (Artemia salina) lethality bioassay.
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Sobre autores
S. Nazneen
Department of Chemistry
Email: sairashahzadi@hotmail.com
Paquistão, Islamabad
S. Ali
Department of Chemistry
Autor responsável pela correspondência
Email: drsa54@hotmail.com
Paquistão, Islamabad, 45320
S. Shahzadi
Department of Chemistry; Department of Chemistry
Autor responsável pela correspondência
Email: sairashahzadi@hotmail.com
Paquistão, Islamabad, 45320; Faisalabad
S. Shujah
Department of Chemistry
Email: sairashahzadi@hotmail.com
Paquistão, Kohat, KPK, 26000
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