Synthesis, spectral, antimicrobial, and thermal properties of Ce(III), Gd(III), Nd(III), Tb(III), and Er(III) gliclazide complexes

Resumo

The complexation between the lanthanide metal ions Ce(III), Gd(III), Nd(III), Tb(III), and Er(III) and gliclazide produced 1 : 1 molar ratio metal: gliclazide (Glz) complexes coordinated in a monodentate fashion via the OH group and having the general formulas [M(Glz)Cl₃(H₂O)]·xH₂O (M = Ce, Gd, Nd and x = 1, 3, 4, respectively) and [M(Glz)(H₂O)₄]Cl₃·yH₂O (M = Tb, Er and y = 1, 2, respectively). The structure of the synthesized lanthanide gliclazide complexes was assigned by IR, ¹HNMR, and UV-Vis spectroscopy. Thermal analysis and kinetic and thermodynamic parameters gave evidence for the thermal stability of the Glz complexes. The latter showed a significant antimicrobial effect against some bacteria and fungi.