Synthesis and antimicrobial screening of novel 9-{2-[(1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione derivatives
- Авторлар: Jalapathi P.1, Kishore Kumar A.1, Sunitha V.1, Shankar B.1, Murali Krishna T.2, Lincoln C.2
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Мекемелер:
- Department of Chemistry
- Department of Biotechnology
- Шығарылым: Том 87, № 9 (2017)
- Беттер: 2011-2020
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221237
- DOI: https://doi.org/10.1134/S1070363217090171
- ID: 221237
Дәйексөз келтіру
Аннотация
A series of novel 9-{2-[(1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione derivatives were synthesized by a click chemistry approach. The structures of all the newly synthesized compounds were characterized by IR, MASS, 1H and 13C NMR spectral data. The final analogues showed good to excellent antibacterial and antifungal activities in an agar well diffusion assay. Compounds 6i and 6f were the most active against all the test bacterial and fungal strains.
Негізгі сөздер
Авторлар туралы
P. Jalapathi
Department of Chemistry
Хат алмасуға жауапты Автор.
Email: pochampalli.ou.chemi@gmail.com
Үндістан, Saifabad, Hyderabad, Telangana, 500004
A. Kishore Kumar
Department of Chemistry
Email: pochampalli.ou.chemi@gmail.com
Үндістан, Saifabad, Hyderabad, Telangana, 500004
V. Sunitha
Department of Chemistry
Email: pochampalli.ou.chemi@gmail.com
Үндістан, Saifabad, Hyderabad, Telangana, 500004
B. Shankar
Department of Chemistry
Email: pochampalli.ou.chemi@gmail.com
Үндістан, Saifabad, Hyderabad, Telangana, 500004
T. Murali Krishna
Department of Biotechnology
Email: pochampalli.ou.chemi@gmail.com
Үндістан, Kishanpura, Hanamkonda, Warangal, Telangana, 506001
Ch. Lincoln
Department of Biotechnology
Email: pochampalli.ou.chemi@gmail.com
Үндістан, Kishanpura, Hanamkonda, Warangal, Telangana, 506001
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