Synthesis and antibacterial activity of novel 4-{4-(methylamino)thieno[3,2- d ]pyrimidin-2-yl}-benzohydrazide derivatives

T. Giri; G. Sailaja; E. Laxminarayana; M. Thirumala Chary; M. Ramesh

doi:10.1134/S1070363217060238

Synthesis and antibacterial activity of novel 4-{4-(methylamino)thieno[3,2-d]pyrimidin-2-yl}-benzohydrazide derivatives

Авторлар: Giri T.¹, Sailaja G.¹, Laxminarayana E.¹, Thirumala Chary M.², Ramesh M.³
Мекемелер:
1. Sreenidhi Institute of Science and Technology (Autonomous)
2. Jawaharlal Nehru Technological University Hyderabad
3. Jawaharlal Nehru Technological University Kakinada
Шығарылым: Том 87, № 6 (2017)
Беттер: 1275-1280
Бөлім: Article
URL: https://journals.rcsi.science/1070-3632/article/view/220339
DOI: https://doi.org/10.1134/S1070363217060238
ID: 220339

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Аннотация

A series of novel 4-{4-(methylamino)thieno[3,2-d]pyrimidin-2-yl}benzohydrazide derivatives were synthesized and evaluated for their antibacterial activity. Most of the compounds demonstrated high activity towards Escherichia coli, Pseudomonas, Staphylococcus aureus, and Bacillus. Structures of all synthesized compounds were confirmed by spectral analysis.