Synthesis and antibacterial activity of novel 4-{4-(methylamino)thieno[3,2-d]pyrimidin-2-yl}-benzohydrazide derivatives
- Authors: Giri T.1, Sailaja G.1, Laxminarayana E.1, Thirumala Chary M.2, Ramesh M.3
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Affiliations:
- Sreenidhi Institute of Science and Technology (Autonomous)
- Jawaharlal Nehru Technological University Hyderabad
- Jawaharlal Nehru Technological University Kakinada
- Issue: Vol 87, No 6 (2017)
- Pages: 1275-1280
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220339
- DOI: https://doi.org/10.1134/S1070363217060238
- ID: 220339
Cite item
Abstract
A series of novel 4-{4-(methylamino)thieno[3,2-d]pyrimidin-2-yl}benzohydrazide derivatives were synthesized and evaluated for their antibacterial activity. Most of the compounds demonstrated high activity towards Escherichia coli, Pseudomonas, Staphylococcus aureus, and Bacillus. Structures of all synthesized compounds were confirmed by spectral analysis.
About the authors
T. Giri
Sreenidhi Institute of Science and Technology (Autonomous)
Email: elxnkits@yahoo.co.in
India, Ghatkesar, Hyderabad, Telangana, 501301
G. Sailaja
Sreenidhi Institute of Science and Technology (Autonomous)
Email: elxnkits@yahoo.co.in
India, Ghatkesar, Hyderabad, Telangana, 501301
E. Laxminarayana
Sreenidhi Institute of Science and Technology (Autonomous)
Author for correspondence.
Email: elxnkits@yahoo.co.in
India, Ghatkesar, Hyderabad, Telangana, 501301
M. Thirumala Chary
Jawaharlal Nehru Technological University Hyderabad
Email: elxnkits@yahoo.co.in
India, Hyderabad, Telangana, 500085
M. Ramesh
Jawaharlal Nehru Technological University Kakinada
Email: elxnkits@yahoo.co.in
India, Kakinada, Telangana, 533003