Diastereotopic derivatives of chiral alkoxyisoindolinones
- Авторлар: Grigoreva T.1, Garabadzhiu A.1, Tribulovich V.1
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Мекемелер:
- St. Petersburg State Institute of Technology (Technical University)
- Шығарылым: Том 86, № 11 (2016)
- Беттер: 2454-2461
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216503
- DOI: https://doi.org/10.1134/S1070363216110098
- ID: 216503
Дәйексөз келтіру
Аннотация
A method for synthesis of 2,3-substituted 3-hydroxyisoindolin-1-one acyl derivatives, modified reactivators of tumor suppressor protein p53, was developed; these compounds were synthesized and characterized. It was shown that diastereomeric esters of Boc-N-protected amino acids, unlike esters with a free amino group, can be preparatively isolated by flash chromatography using achiral media.
Негізгі сөздер
Авторлар туралы
T. Grigoreva
St. Petersburg State Institute of Technology (Technical University)
Хат алмасуға жауапты Автор.
Email: rozentatiana@gmail.com
Ресей, Moskovskii pr. 26, St. Petersburg, 190013
A. Garabadzhiu
St. Petersburg State Institute of Technology (Technical University)
Email: rozentatiana@gmail.com
Ресей, Moskovskii pr. 26, St. Petersburg, 190013
V. Tribulovich
St. Petersburg State Institute of Technology (Technical University)
Email: rozentatiana@gmail.com
Ресей, Moskovskii pr. 26, St. Petersburg, 190013
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