Solvent-free microwave assisted synthesis of morpholine–piperidine–pyrrolidine annulated quinoline-naphthyl based chalcones and their antimicrobial activity
- Авторлар: Ashok D.1, Elsanoosi M.1, Alanab B.1, Sarasija M.1, Ravi S.1
-
Мекемелер:
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Шығарылым: Том 86, № 5 (2016)
- Беттер: 1120-1125
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215009
- DOI: https://doi.org/10.1134/S1070363216050236
- ID: 215009
Дәйексөз келтіру
Аннотация
A new series of 2-morpholine–piperidine–pyrrolidine substituted quinoline based chalcones have been synthesized by conventional and microwave irradiation methods. All synthesized compounds were characterised by IR, 1H and 13C NMR, mass spectrometry, and elemental analysis. The products were evaluated in vitro for antibacterial activity against two bacterial strains (Staphylococcus aureus, Escherichia coli) and antifungal activity against two fungal strains (Aspergillus flavus, Candida metapsilosis). 2-Piperidine substituted quinoline chalcones demonstrated high antimicrobial activity.
Авторлар туралы
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Хат алмасуға жауапты Автор.
Email: ashokdou@gmail.com
Үндістан, Hyderabad, 500007
M. Elsanoosi
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Үндістан, Hyderabad, 500007
B. Alanab
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Үндістан, Hyderabad, 500007
M. Sarasija
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Үндістан, Hyderabad, 500007
S. Ravi
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Үндістан, Hyderabad, 500007
![](/img/style/loading.gif)