Solvent-free microwave assisted synthesis of morpholine–piperidine–pyrrolidine annulated quinoline-naphthyl based chalcones and their antimicrobial activity
- Авторы: Ashok D.1, Elsanoosi M.1, Alanab B.1, Sarasija M.1, Ravi S.1
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Учреждения:
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Выпуск: Том 86, № 5 (2016)
- Страницы: 1120-1125
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215009
- DOI: https://doi.org/10.1134/S1070363216050236
- ID: 215009
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Аннотация
A new series of 2-morpholine–piperidine–pyrrolidine substituted quinoline based chalcones have been synthesized by conventional and microwave irradiation methods. All synthesized compounds were characterised by IR, 1H and 13C NMR, mass spectrometry, and elemental analysis. The products were evaluated in vitro for antibacterial activity against two bacterial strains (Staphylococcus aureus, Escherichia coli) and antifungal activity against two fungal strains (Aspergillus flavus, Candida metapsilosis). 2-Piperidine substituted quinoline chalcones demonstrated high antimicrobial activity.
Об авторах
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Автор, ответственный за переписку.
Email: ashokdou@gmail.com
Индия, Hyderabad, 500007
M. Elsanoosi
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Индия, Hyderabad, 500007
B. Alanab
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Индия, Hyderabad, 500007
M. Sarasija
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Индия, Hyderabad, 500007
S. Ravi
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
Индия, Hyderabad, 500007
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