Synthesis and Antimicrobial Activity of (E)-2-[(1-Substituted Phenyl-1H-1,2,3-triazol-4-yl)methylene]-2,3-dihydro-1H-inden-1-ones
- Authors: Swamy M.K.1, Swapna M.1, Sandeep T.1, Venkateswar Rao P.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 89, No 9 (2019)
- Pages: 1884-1886
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223088
- DOI: https://doi.org/10.1134/S107036321909024X
- ID: 223088
Cite item
Abstract
A series of novel (E)-2-[(1-phenyl-1H-1,2,3-triazol-4-yl)methylene]-2,3-dihydro-1H-inden-1-one derivatives has been synthesized by condensation of 1-phenyl-1H-1,2,3-triazole-4-carbaldehydes with 2,3-dihydro-1H-inden-1-one. The synthesized compounds are characterized by 1H and 13C NMR, and mass spectrometry, and tested in vitro against four bacterial organism and two fungal organisms. The tests data demonstrate moderate to good activity of the compounds.
About the authors
M. K. Swamy
Department of Chemistry
Email: pallapothulavrao@gmail.com
India, Hyderabad, 500007
M. Swapna
Department of Chemistry
Email: pallapothulavrao@gmail.com
India, Hyderabad, 500007
T. Sandeep
Department of Chemistry
Email: pallapothulavrao@gmail.com
India, Hyderabad, 500007
P. Venkateswar Rao
Department of Chemistry
Author for correspondence.
Email: pallapothulavrao@gmail.com
India, Hyderabad, 500007
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