New Acylhydrazones of Indole Series and Their Metal Complexes
- Authors: Vikrishchuk N.I.1, Popov L.D.1, Borodkin G.S.2, Dranikova A.Y.2, Kletskii M.E.1, Zagrebaev A.D.1, Burov O.N.1
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Affiliations:
- Southern Federal University
- Research Institute of Physical and Organic Chemistry of Southern Federal University
- Issue: Vol 88, No 5 (2018)
- Pages: 962-967
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222193
- DOI: https://doi.org/10.1134/S1070363218050213
- ID: 222193
Cite item
Abstract
By the reaction of 2-chloroindole-3-carbaldehyde with acylhydrazones new acylhydrazones of the indole series have been synthesized, and their structure, the possibility of cyclization to pyrazoloindoles, and complexing properties have been studied. By means of quantum chemical DFT calculations taking into account the solvent effect it was shown that the reaction of 2-chloroindole-3-carbaldehyde and the corresponding acylhydrazine is an exothermic process, irrespective of which final product is formed, indolemethylenehydrazide or pyrazoloindole. Therefore, both possible transformations in the studied reacting system are controlled kinetically and not thermodynamically.
Keywords
About the authors
N. I. Vikrishchuk
Southern Federal University
Author for correspondence.
Email: natvi2004@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090
L. D. Popov
Southern Federal University
Email: natvi2004@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090
G. S. Borodkin
Research Institute of Physical and Organic Chemistry of Southern Federal University
Email: natvi2004@mail.ru
Russian Federation, Rostov-on-Don
A. Yu. Dranikova
Research Institute of Physical and Organic Chemistry of Southern Federal University
Email: natvi2004@mail.ru
Russian Federation, Rostov-on-Don
M. E. Kletskii
Southern Federal University
Email: natvi2004@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090
A. D. Zagrebaev
Southern Federal University
Email: natvi2004@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090
O. N. Burov
Southern Federal University
Email: natvi2004@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090