2-Cyano-3-(dimethylamino)prop-2-ene Thioamide: A New Reagent for Synthesis of Functionalized 4-Unsubstituted Ethyl Nicotinates and Nicotinonitriles


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Abstract

Condensation of cyclopent(hex)ylidenecyanothioacetamide with N, N-dimethylformamide dimethyl acetal led to the formation of a new reagent for organic synthesis: 2-cyano-3-(dimethylamino)prop-2-ene thioamide. On its basis a series of ethyl nicotinates and nicotinonitriles were synthesized by a vinyl substitution reaction.

About the authors

I. V. Dyachenko

Taras Shevchenko Lugansk National University

Author for correspondence.
Email: ivladya87@mail.ru
Ukraine, ul. Oboronnaya 2, Lugansk, 91011


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