Highly Efficiently Synthesis of Disubstituted Pyrrole Derivatives via Rh(III)-Catalyzed Direct C–H Alkylation Under Mild Conditions
- Authors: Wang L.1, Li Z.1, Qu X.1, Peng W.M.1, Hu S.Q.1, Wang F.2
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Affiliations:
- Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering
- College of Chemistry and Materials Science
- Issue: Vol 88, No 4 (2018)
- Pages: 758-766
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222143
- DOI: https://doi.org/10.1134/S1070363218040217
- ID: 222143
Cite item
Abstract
A mild and highly efficient Rh(III)-catalyzed direct C–H alkylation of pyrroles with diazo compounds has been developed. This green and atom-economic catalytic process enables an efficient access to various densely functionalized pyrrole derivatives in good to excellent yields, and it is potentially applicable to the large-scale synthesis of pyrrole derivatives.
Keywords
About the authors
L. Wang
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering
Author for correspondence.
Email: wangliang@mail.jhun.edu.cn
China, Wuhan, 430056
Zh. Li
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering
Email: wangliang@mail.jhun.edu.cn
China, Wuhan, 430056
X. Qu
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering
Email: wangliang@mail.jhun.edu.cn
China, Wuhan, 430056
W. M. Peng
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering
Email: wangliang@mail.jhun.edu.cn
China, Wuhan, 430056
Si Q. Hu
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering
Email: wangliang@mail.jhun.edu.cn
China, Wuhan, 430056
F. Wang
College of Chemistry and Materials Science
Email: wangliang@mail.jhun.edu.cn
China, Xiaogan, 432000