Email this article Synthesis and Characterization of Disulfide-Schiff Base Derivatives and in vitro Investigation of Their Antibacterial Activity Against Multidrug-Resistant Acinetobacter baumannii Isolates: A New Study
- Authors: Durmus S.1, Dalmaz A.2, Calıskan E.3, Dulger G.4
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Affiliations:
- Department of Chemistry, Faculty of Science and Arts
- Department of Chemistry, Graduate School Natural and Applied Sciences
- Department of Medical Microbiology, Faculty of Medicine
- Department of Medical Biology, Faculty of Medicine, Duzce University
- Issue: Vol 88, No 2 (2018)
- Pages: 305-311
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222012
- DOI: https://doi.org/10.1134/S1070363218020184
- ID: 222012
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Abstract
In this study two different methods without a catalyst and with a CeO2 nano catalyst were used for the synthesis of dimeric disulfide-Schiff bases. The dimeric disulfide-Schiff base derivatives were characterized by FT-IR, NMR, and MS spectra, and elemental analysis. The disulfide-Schiff bases and their derivatives 2–5c were screened for in vitro antibacterial activity against 40 multidrug-resistant strains of Acinetobacter baumannii, and their minimum inhibitory concentrations were determined. Most of products exhibited high antibacterial activity against Acinetobacter baumannii.
About the authors
S. Durmus
Department of Chemistry, Faculty of Science and Arts
Author for correspondence.
Email: sefadurmus67@gmail.com
Turkey, Konuralp, Duzce, 81620
A. Dalmaz
Department of Chemistry, Graduate School Natural and Applied Sciences
Email: sefadurmus67@gmail.com
Turkey, Konuralp, Duzce, 81620
E. Calıskan
Department of Medical Microbiology, Faculty of Medicine
Email: sefadurmus67@gmail.com
Turkey, Konuralp, Duzce, 81620
G. Dulger
Department of Medical Biology, Faculty of Medicine, Duzce University
Email: sefadurmus67@gmail.com
Turkey, Konuralp, Duzce, 81620
