Email this article The Schiff bases of pyridoxal-5-phosphate and hydrazides of certain pyrazoles: Stability, kinetics of formation, and synthesis
- Authors: Gamov G.A.1, Aleksandriiskii V.V.1,2, Zavalishin M.N.1, Khokhlova A.Y.1, Sharnin V.A.1,2
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Affiliations:
- Ivanovo State University of Chemistry and Technology
- Krestov Institute of Solutions Chemistry
- Issue: Vol 87, No 6 (2017)
- Pages: 1161-1166
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220158
- DOI: https://doi.org/10.1134/S1070363217060093
- ID: 220158
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Abstract
The interaction of pyridoxal-5-phosphate with 3-methyl-1Н-pyrazole-5-carbohydrazide, 2-(3,5-dimethyl-1Н-pyrazol-4-yl)acetohydrazide, and 1Н-pyrazole-3-carbohydrazide has yielded Schiff bases; the products have been characterized by 1Н NMR and IR spectra. The binding ability of these pyrazoles with respect to pyridoxal-5-phosphate under conditions modeling the living tissues has been evaluated. Rate constants of the formation of the Schiff bases have been determined.
About the authors
G. A. Gamov
Ivanovo State University of Chemistry and Technology
Author for correspondence.
Email: georgegamov38@gmail.com
Russian Federation, Sheremetevskii pr. 7, Ivanovo, 153000
V. V. Aleksandriiskii
Ivanovo State University of Chemistry and Technology; Krestov Institute of Solutions Chemistry
Email: georgegamov38@gmail.com
Russian Federation, Sheremetevskii pr. 7, Ivanovo, 153000; Ivanovo
M. N. Zavalishin
Ivanovo State University of Chemistry and Technology
Email: georgegamov38@gmail.com
Russian Federation, Sheremetevskii pr. 7, Ivanovo, 153000
A. Yu. Khokhlova
Ivanovo State University of Chemistry and Technology
Email: georgegamov38@gmail.com
Russian Federation, Sheremetevskii pr. 7, Ivanovo, 153000
V. A. Sharnin
Ivanovo State University of Chemistry and Technology; Krestov Institute of Solutions Chemistry
Email: georgegamov38@gmail.com
Russian Federation, Sheremetevskii pr. 7, Ivanovo, 153000; Ivanovo
