The Schiff bases of pyridoxal-5-phosphate and hydrazides of certain pyrazoles: Stability, kinetics of formation, and synthesis
- Autores: Gamov G.1, Aleksandriiskii V.1,2, Zavalishin M.1, Khokhlova A.1, Sharnin V.1,2
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Afiliações:
- Ivanovo State University of Chemistry and Technology
- Krestov Institute of Solutions Chemistry
- Edição: Volume 87, Nº 6 (2017)
- Páginas: 1161-1166
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220158
- DOI: https://doi.org/10.1134/S1070363217060093
- ID: 220158
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Resumo
The interaction of pyridoxal-5-phosphate with 3-methyl-1Н-pyrazole-5-carbohydrazide, 2-(3,5-dimethyl-1Н-pyrazol-4-yl)acetohydrazide, and 1Н-pyrazole-3-carbohydrazide has yielded Schiff bases; the products have been characterized by 1Н NMR and IR spectra. The binding ability of these pyrazoles with respect to pyridoxal-5-phosphate under conditions modeling the living tissues has been evaluated. Rate constants of the formation of the Schiff bases have been determined.
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Sobre autores
G. Gamov
Ivanovo State University of Chemistry and Technology
Autor responsável pela correspondência
Email: georgegamov38@gmail.com
Rússia, Sheremetevskii pr. 7, Ivanovo, 153000
V. Aleksandriiskii
Ivanovo State University of Chemistry and Technology; Krestov Institute of Solutions Chemistry
Email: georgegamov38@gmail.com
Rússia, Sheremetevskii pr. 7, Ivanovo, 153000; Ivanovo
M. Zavalishin
Ivanovo State University of Chemistry and Technology
Email: georgegamov38@gmail.com
Rússia, Sheremetevskii pr. 7, Ivanovo, 153000
A. Khokhlova
Ivanovo State University of Chemistry and Technology
Email: georgegamov38@gmail.com
Rússia, Sheremetevskii pr. 7, Ivanovo, 153000
V. Sharnin
Ivanovo State University of Chemistry and Technology; Krestov Institute of Solutions Chemistry
Email: georgegamov38@gmail.com
Rússia, Sheremetevskii pr. 7, Ivanovo, 153000; Ivanovo