Email this article Synthesis and antibacterial activity of novel pyrano[2,3-d]pyrimidine-4-one–3-phenylisoxazole hybrids
- Authors: Kumar B.S.1, Lakshmi P.V.1, Veena B.S.2, Sujatha E.2
-
Affiliations:
- Department of Chemistry, University College for Women
- Department of Botany, University College of Science
- Issue: Vol 87, No 4 (2017)
- Pages: 829-836
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219413
- DOI: https://doi.org/10.1134/S1070363217040260
- ID: 219413
Cite item
Open Access
Access granted
Subscription Access
Abstract
A series of ethyl 2,7-dimethyl-4-oxo-5-phenyl-3-[(3-phenylisoxazol-5-yl)methyl]-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine-6-carboxylates was synthesized and screened for antibacterial activity against Gram positive and Gram negative bacterial species. All new compounds were characterized by 1H, 13C NMR, IR, and mass spectra. The results of the antibacterial study indicated that all compounds exhibited good to excellent antibacterial activity.
About the authors
B. S. Kumar
Department of Chemistry, University College for Women
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
P. V. A. Lakshmi
Department of Chemistry, University College for Women
Author for correspondence.
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
B. S. Veena
Department of Botany, University College of Science
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
E. Sujatha
Department of Botany, University College of Science
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
