Synthesis and antibacterial activity of novel pyrano[2,3-d]pyrimidine-4-one–3-phenylisoxazole hybrids
- Autores: Kumar B.1, Lakshmi P.1, Veena B.2, Sujatha E.2
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Afiliações:
- Department of Chemistry, University College for Women
- Department of Botany, University College of Science
- Edição: Volume 87, Nº 4 (2017)
- Páginas: 829-836
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219413
- DOI: https://doi.org/10.1134/S1070363217040260
- ID: 219413
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Resumo
A series of ethyl 2,7-dimethyl-4-oxo-5-phenyl-3-[(3-phenylisoxazol-5-yl)methyl]-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine-6-carboxylates was synthesized and screened for antibacterial activity against Gram positive and Gram negative bacterial species. All new compounds were characterized by 1H, 13C NMR, IR, and mass spectra. The results of the antibacterial study indicated that all compounds exhibited good to excellent antibacterial activity.
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Sobre autores
B. Kumar
Department of Chemistry, University College for Women
Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007
P. Lakshmi
Department of Chemistry, University College for Women
Autor responsável pela correspondência
Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007
B. Veena
Department of Botany, University College of Science
Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007
E. Sujatha
Department of Botany, University College of Science
Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007