Homobimetallic organotin(IV) complexes with succinohydrazide Schiff base: Synthesis, spectroscopic characterization, and biological screening
- Authors: Shujah S.1, Khalid N.2, Ali S.1
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Affiliations:
- Department of Chemistry
- Chemistry Division
- Issue: Vol 87, No 3 (2017)
- Pages: 515-522
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218875
- DOI: https://doi.org/10.1134/S1070363217030227
- ID: 218875
Cite item
Abstract
Six new bis-diorganotin(IV) complexes, [(Me2Sn)2L] (1), [(Et2Sn)2L] (2), [(n-Bu2Sn)2L] (3), [(Ph2Sn)2L] (4), [(n-Oct2Sn)2L] (5), and [(tert-C4H9)2Sn)2L] (6), where L = N1',N4'-bis(2-oxidobenzylidene)-succinohydrazide, were synthesized and characterized by elemental analysis, FT-IR, NMR (1H, 13C, and 119Sn) and Mass spectra. Spectroscopic data authenticated the existence of two pentacoordinated tin centers in all complexes, formed via coordination of bis-ONO donor sites with dialkyltin(IV) moieties. Biological screening against selected pathogenic strains of bacteria and fungi revealed high activity of compound 3 against Bacillus subtilis and Aspergillus flavis, it also exhibited highest cytotoxicity against Artemia salina.
About the authors
S. Shujah
Department of Chemistry; Department of Chemistry
Author for correspondence.
Email: shaukat.shujah@yahoo.com
Pakistan, Kohat, 26000; Islamabad, 45320
N. Khalid
Chemistry Division
Email: shaukat.shujah@yahoo.com
Pakistan, Islamabad
S. Ali
Department of Chemistry
Email: shaukat.shujah@yahoo.com
Pakistan, Islamabad, 45320