Catalytic alkylation of cycloalkaneindoles and tetrahydro-γ-carboline with 9-oxiranylmethylcarbazole
- Authors: Sokolov V.B.1, Aksinenko A.Y.1, Epishina T.A.1, Goreva T.V.1
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Affiliations:
- Institute of Physiologically Active Compounds
- Issue: Vol 86, No 8 (2016)
- Pages: 1827-1831
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215912
- DOI: https://doi.org/10.1134/S1070363216080089
- ID: 215912
Cite item
Abstract
Catalytic alkylation of substituted indoles such as cycloalkaneindoles and tetrahydro-γ-carboline using 9-oxiranylmethylcarbazole leads to the formation of 1-(carbazol-9-yl)-3-{dihydrocycloalkane[b]indol-4(1H)-yl}propan-2-ols and 1-(carbazol-9-yl)-3-{2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl}propan-2-ol, conjugates containing 2-hydroxypropylene spacer.
About the authors
V. B. Sokolov
Institute of Physiologically Active Compounds
Email: alaks@ipac.ac.ru
Russian Federation, Severniy pr. 1, Chernogolovka, 142432
A. Yu. Aksinenko
Institute of Physiologically Active Compounds
Author for correspondence.
Email: alaks@ipac.ac.ru
Russian Federation, Severniy pr. 1, Chernogolovka, 142432
T. A. Epishina
Institute of Physiologically Active Compounds
Email: alaks@ipac.ac.ru
Russian Federation, Severniy pr. 1, Chernogolovka, 142432
T. V. Goreva
Institute of Physiologically Active Compounds
Email: alaks@ipac.ac.ru
Russian Federation, Severniy pr. 1, Chernogolovka, 142432
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