Email this article Aryl ethers of 4-[(2-hydroxyethyl)sulfanyl]pyrimidine derivatives: Pathways of synthesis and fungicidal activity of their salt forms
- Authors: Erkin A.V.1, Klaptyuk I.V.2, Gurzhii V.V.3, Yuzikhin O.S.4, Krutikov V.I.1
-
Affiliations:
- St. Petersburg State Institute of Technology (Technical University), Moskovskii pr. 26
- St. Petersburg University of State Fire Service at the Emergency Situations Ministry of Russian Federation
- St. Petersburg State University
- Kirov St. Petersburg State Forest Technical University
- Issue: Vol 86, No 6 (2016)
- Pages: 1274-1281
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215234
- DOI: https://doi.org/10.1134/S1070363216060098
- ID: 215234
Cite item
Open Access
Access granted
Subscription Access
Abstract
2-Amino-4-[(2-aryloxyethyl)sulfanyl]-6-methylpyrimidines were obtained by S-alkylation of 2-amino-6-methylpyrimidin-4(3H)-thione with 2-aryloxyethyl chlorides. Since 2-amino-4-[(2-chloroethyl)sulfanyl]-6-methylpyrimidine is prone to in situ intramolecular cyclization it cannot be used in Claisen reaction. The bromination of the target compounds provided 5-bromo derivatives; some of their hydrochlorides exhibited fungicidal activity.
About the authors
A. V. Erkin
St. Petersburg State Institute of Technology (Technical University), Moskovskii pr. 26
Email: kruerk@yandex.ru
Russian Federation, St. Petersburg, 190013
I. V. Klaptyuk
St. Petersburg University of State Fire Service at the Emergency Situations Ministry of Russian Federation
Email: kruerk@yandex.ru
Russian Federation, St. Petersburg
V. V. Gurzhii
St. Petersburg State University
Email: kruerk@yandex.ru
Russian Federation, St. Petersburg
O. S. Yuzikhin
Kirov St. Petersburg State Forest Technical University
Email: kruerk@yandex.ru
Russian Federation, St. Petersburg
V. I. Krutikov
St. Petersburg State Institute of Technology (Technical University), Moskovskii pr. 26
Author for correspondence.
Email: kruerk@yandex.ru
Russian Federation, St. Petersburg, 190013
