Synthesis and antibacterial activity of some new benzo[5,6]chromeno[2,3-d]pyrimidines
- 作者: Ameli S.1, Pordel M.1, Davoodnia A.1, Jajarmi M.1
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隶属关系:
- Department of Chemistry, Mashhad Branch
- 期: 卷 43, 编号 4 (2017)
- 页面: 429-434
- 栏目: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/228597
- DOI: https://doi.org/10.1134/S1068162017040100
- ID: 228597
如何引用文章
详细
The synthesis and antibacterial activity of some new benzo[5,6]chromeno[2,3-d]pyrimidine derivatives are described. The title compounds were obtained by the reaction of 1H-benzo[f]chromenes with aliphatic and aromatic amines. The structures of all newly synthesized compounds were confirmed by IR, 1HNMR, 13C NMR, and NOESY experiments. The compounds exhibited potent antibacterial activity against gram-positive and gram-negative bacterial species. 10-Methyl-12-(4-hydroxyphenyl)-10,12-dihydro-11H-benzo[5,6]chromeno[2,3-d] pyrimidin-11-imine displayed greater antibacterial activity against gramnegative bacterial species than did ciprofloxacinandamoxicillin.
作者简介
Shohreh Ameli
Department of Chemistry, Mashhad Branch
Email: mehdipordel58@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9187147578
Mehdi Pordel
Department of Chemistry, Mashhad Branch
编辑信件的主要联系方式.
Email: mehdipordel58@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9187147578
Abolghasem Davoodnia
Department of Chemistry, Mashhad Branch
Email: mehdipordel58@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9187147578
Maryam Jajarmi
Department of Chemistry, Mashhad Branch
Email: mehdipordel58@mshdiau.ac.ir
伊朗伊斯兰共和国, Mashhad, 9187147578