Synthesis and antibacterial activity of some new benzo[5,6]chromeno[2,3-d]pyrimidines
- Авторлар: Ameli S.1, Pordel M.1, Davoodnia A.1, Jajarmi M.1
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Мекемелер:
- Department of Chemistry, Mashhad Branch
- Шығарылым: Том 43, № 4 (2017)
- Беттер: 429-434
- Бөлім: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/228597
- DOI: https://doi.org/10.1134/S1068162017040100
- ID: 228597
Дәйексөз келтіру
Аннотация
The synthesis and antibacterial activity of some new benzo[5,6]chromeno[2,3-d]pyrimidine derivatives are described. The title compounds were obtained by the reaction of 1H-benzo[f]chromenes with aliphatic and aromatic amines. The structures of all newly synthesized compounds were confirmed by IR, 1HNMR, 13C NMR, and NOESY experiments. The compounds exhibited potent antibacterial activity against gram-positive and gram-negative bacterial species. 10-Methyl-12-(4-hydroxyphenyl)-10,12-dihydro-11H-benzo[5,6]chromeno[2,3-d] pyrimidin-11-imine displayed greater antibacterial activity against gramnegative bacterial species than did ciprofloxacinandamoxicillin.
Негізгі сөздер
Авторлар туралы
Shohreh Ameli
Department of Chemistry, Mashhad Branch
Email: mehdipordel58@mshdiau.ac.ir
Иран, Mashhad, 9187147578
Mehdi Pordel
Department of Chemistry, Mashhad Branch
Хат алмасуға жауапты Автор.
Email: mehdipordel58@mshdiau.ac.ir
Иран, Mashhad, 9187147578
Abolghasem Davoodnia
Department of Chemistry, Mashhad Branch
Email: mehdipordel58@mshdiau.ac.ir
Иран, Mashhad, 9187147578
Maryam Jajarmi
Department of Chemistry, Mashhad Branch
Email: mehdipordel58@mshdiau.ac.ir
Иран, Mashhad, 9187147578