Conformationally locked GFP chromophore derivatives as potential fluorescent sensors
- 作者: Baleeva N.1, Yampolsky I.1,2, Baranov M.1,2
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隶属关系:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Pirogov Russian National Research Medical University
- 期: 卷 42, 编号 4 (2016)
- 页面: 453-456
- 栏目: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/228078
- DOI: https://doi.org/10.1134/S1068162016040051
- ID: 228078
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详细
We propose to use the conformationally locked GFP chromophore derivatives (4-(2(difluoroboryl)benzylidene)-1H-imidazol-5(4H)-ones) as potential fluorescent sensors. The model carbamate derivatives were synthesized and their fluorescent properties were studied. It was shown that the introduction/cleavage of the carbamate groups at the nitrogen atom led to the noticeable shifts in the absorption and emission maxima of the resultant derivatives, which makes them promising candidates for new fluorescent sensors.
作者简介
N. Baleeva
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: baranovmikes@gmail.com
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997
I. Yampolsky
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pirogov Russian National Research Medical University
Email: baranovmikes@gmail.com
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Ostrovityanova 1, Moscow, 117997
M. Baranov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pirogov Russian National Research Medical University
编辑信件的主要联系方式.
Email: baranovmikes@gmail.com
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Ostrovityanova 1, Moscow, 117997