Conformationally locked GFP chromophore derivatives as potential fluorescent sensors
- Авторы: Baleeva N.1, Yampolsky I.1,2, Baranov M.1,2
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Учреждения:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Pirogov Russian National Research Medical University
- Выпуск: Том 42, № 4 (2016)
- Страницы: 453-456
- Раздел: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/228078
- DOI: https://doi.org/10.1134/S1068162016040051
- ID: 228078
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Аннотация
We propose to use the conformationally locked GFP chromophore derivatives (4-(2(difluoroboryl)benzylidene)-1H-imidazol-5(4H)-ones) as potential fluorescent sensors. The model carbamate derivatives were synthesized and their fluorescent properties were studied. It was shown that the introduction/cleavage of the carbamate groups at the nitrogen atom led to the noticeable shifts in the absorption and emission maxima of the resultant derivatives, which makes them promising candidates for new fluorescent sensors.
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Об авторах
N. Baleeva
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: baranovmikes@gmail.com
Россия, ul. Miklukho-Maklaya 16/10, Moscow, 117997
I. Yampolsky
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pirogov Russian National Research Medical University
Email: baranovmikes@gmail.com
Россия, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Ostrovityanova 1, Moscow, 117997
M. Baranov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Pirogov Russian National Research Medical University
Автор, ответственный за переписку.
Email: baranovmikes@gmail.com
Россия, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Ostrovityanova 1, Moscow, 117997