Мақаланы E-mail арқылы жіберу Optimization of Fungal Luciferin Synthesis
- Авторлар: Bubyrev A.1, Tsarkova A.1,2, Kaskova Z.1,2
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Мекемелер:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Pirogov Russian National Research Medical University
- Шығарылым: Том 45, № 2 (2019)
- Беттер: 183-185
- Бөлім: Letter to Editor
- URL: https://journals.rcsi.science/1068-1620/article/view/229189
- DOI: https://doi.org/10.1134/S106816201902002X
- ID: 229189
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Current studies of fungal bioluminescent systems, including the purification of luciferase, require large quantities of the synthetic substrate luciferin available. The existing synthetic method for the luciferin produces low yield of the target molecule. In the current work, the synthesis of fungal luciferin was scaled up to gram quantities and an effective method for its final purification was found. The total yield in comparison with the previous method was increased by 3.5 times; the overall cost of synthesis fell by 3 times.
Авторлар туралы
A. Bubyrev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: zkaskova@ibch.ru
Ресей, Moscow, 117997
A. Tsarkova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences; Pirogov Russian National Research Medical University
Email: zkaskova@ibch.ru
Ресей, Moscow, 117997; Moscow, 117997
Z. Kaskova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences; Pirogov Russian National Research Medical University
Хат алмасуға жауапты Автор.
Email: zkaskova@ibch.ru
Ресей, Moscow, 117997; Moscow, 117997
