Мақаланы E-mail арқылы жіберу Study of the Carbohydrate Specificity of Antibodies Against Aspergillus fumigatus Using the Library of Synthetic Mycoantigens
- Авторлар: Krylov V.B.1, Petruk M.I.1, Grigoryev I.V.2, Lebedin Y.S.2, Glushko N.I.3, Khaldeeva E.V.3, Argunov D.A.1, Khatuntseva E.A.1, Toplishek M.V.1, Komarova B.S.1, Karelin A.A.1, Yudina O.N.1, Menshov V.M.1, Yashunskii D.V.1, Tsvetkov Y.E.1, Nifantiev N.E.1
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Мекемелер:
- Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
- XEMA Company Limited
- Kazan Scientific Research Institute of Epidemiology and Microbiology
- Шығарылым: Том 44, № 1 (2018)
- Беттер: 80-89
- Бөлім: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/228804
- DOI: https://doi.org/10.1134/S1068162017060073
- ID: 228804
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The carbohydrate specificity of antibodies obtained by immunizing laboratory animals with immunogens prepared from the Aspergillus fumigatus cell wall was analyzed using the library of biotinylated synthetic oligosaccharides. It has been shown that the main part of antipolysaccharide antibodies recognizes galactomannan in the studied immunogens with preference to its fragments containing more than two β-(1→5)-linked galactofuranosyl units. The data obtained can form the basis for the development of enzyme immunoassay for the detection of this dangerous fungal pathogen.
Негізгі сөздер
Авторлар туралы
V. Krylov
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
M. Petruk
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
I. Grigoryev
XEMA Company Limited
Email: nen@ioc.ac.ru
Ресей, Moscow, 105264
Y. Lebedin
XEMA Company Limited
Email: nen@ioc.ac.ru
Ресей, Moscow, 105264
N. Glushko
Kazan Scientific Research Institute of Epidemiology and Microbiology
Email: nen@ioc.ac.ru
Ресей, Kazan, 420015
E. Khaldeeva
Kazan Scientific Research Institute of Epidemiology and Microbiology
Email: nen@ioc.ac.ru
Ресей, Kazan, 420015
D. Argunov
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
E. Khatuntseva
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
M. Toplishek
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
B. Komarova
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
A. Karelin
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
O. Yudina
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
V. Menshov
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
D. Yashunskii
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
Y. Tsvetkov
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
N. Nifantiev
Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry
Хат алмасуға жауапты Автор.
Email: nen@ioc.ac.ru
Ресей, Moscow, 119991
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