Methyl N-(carbazolyl)acetyl-2-aminotetrahydrobenzothiophene-3-carboxylates as modulators of NMDA receptors


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Methyl N-(carbazolyl)acetyl-2-aminotetrahydrothiophene-3-carboxylates were synthesized by alkylation of carbazoles with the corresponding chloroacetylamides of 2-aminotiophenes. The radioligand binding method showed the presence of the modulating effect of the synthesized compounds on the neuronal NMDA receptors.

作者简介

V. Sokolov

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

A. Aksinenko

Institute of Physiologically Active Compounds, Russian Academy of Sciences

编辑信件的主要联系方式.
Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

A. Gabrel’yan

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

V. Grigoriev

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432


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