Methyl N-(carbazolyl)acetyl-2-aminotetrahydrobenzothiophene-3-carboxylates as modulators of NMDA receptors
- 作者: Sokolov V.1, Aksinenko A.1, Gabrel’yan A.1, Grigoriev V.1
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隶属关系:
- Institute of Physiologically Active Compounds, Russian Academy of Sciences
- 期: 卷 68, 编号 8 (2019)
- 页面: 1629-1632
- 栏目: Full Article
- URL: https://journals.rcsi.science/1066-5285/article/view/243463
- DOI: https://doi.org/10.1007/s11172-019-2602-4
- ID: 243463
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详细
Methyl N-(carbazolyl)acetyl-2-aminotetrahydrothiophene-3-carboxylates were synthesized by alkylation of carbazoles with the corresponding chloroacetylamides of 2-aminotiophenes. The radioligand binding method showed the presence of the modulating effect of the synthesized compounds on the neuronal NMDA receptors.
作者简介
V. Sokolov
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
A. Aksinenko
Institute of Physiologically Active Compounds, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
A. Gabrel’yan
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
V. Grigoriev
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Email: alaks@ipac.ac.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432