Enviar artigo por via de e-mail Methyl N-(carbazolyl)acetyl-2-aminotetrahydrobenzothiophene-3-carboxylates as modulators of NMDA receptors
- Autores: Sokolov V.1, Aksinenko A.1, Gabrel’yan A.1, Grigoriev V.1
-
Afiliações:
- Institute of Physiologically Active Compounds, Russian Academy of Sciences
- Edição: Volume 68, Nº 8 (2019)
- Páginas: 1629-1632
- Seção: Full Article
- URL: https://journals.rcsi.science/1066-5285/article/view/243463
- DOI: https://doi.org/10.1007/s11172-019-2602-4
- ID: 243463
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
Methyl N-(carbazolyl)acetyl-2-aminotetrahydrothiophene-3-carboxylates were synthesized by alkylation of carbazoles with the corresponding chloroacetylamides of 2-aminotiophenes. The radioligand binding method showed the presence of the modulating effect of the synthesized compounds on the neuronal NMDA receptors.
Sobre autores
V. Sokolov
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
A. Aksinenko
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Autor responsável pela correspondência
Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
A. Gabrel’yan
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
V. Grigoriev
Institute of Physiologically Active Compounds, Russian Academy of Sciences
Email: alaks@ipac.ac.ru
Rússia, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
