Methyl N-(carbazolyl)acetyl-2-aminotetrahydrobenzothiophene-3-carboxylates as modulators of NMDA receptors


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Аннотация

Methyl N-(carbazolyl)acetyl-2-aminotetrahydrothiophene-3-carboxylates were synthesized by alkylation of carbazoles with the corresponding chloroacetylamides of 2-aminotiophenes. The radioligand binding method showed the presence of the modulating effect of the synthesized compounds on the neuronal NMDA receptors.

Авторлар туралы

V. Sokolov

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Ресей, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

A. Aksinenko

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Хат алмасуға жауапты Автор.
Email: alaks@ipac.ac.ru
Ресей, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

A. Gabrel’yan

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Ресей, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

V. Grigoriev

Institute of Physiologically Active Compounds, Russian Academy of Sciences

Email: alaks@ipac.ac.ru
Ресей, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432

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