A study of the viscosity of hyaluronic acid solutions for the preparation of polyelectrolyte complexes with chitosan


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The viscosity of hyaluronic acid solutions kept at different pH values was found to decrease in the following order of pH: 6.5 > 3.5 > 4.3, although acid hydrolysis occurred at a higher rate in the most acidic solution. The poorest stability of the solutions with pH 4.3 was attributed to the compaction of the macromolecules as a result of charge density redistribution along the polyacid chains.

作者简介

S. Uspenskii

N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences

编辑信件的主要联系方式.
Email: s.a.uspenskii@mail.ru
俄罗斯联邦, 70 ul. Profsoyuznaya, Moscow, 117393

N. Kil’deeva

Moscow State University of Design and Technology

Email: s.a.uspenskii@mail.ru
俄罗斯联邦, 33 ul. Sadovnicheskaya, Moscow, 117997

M. Maslova

Moscow State University of Design and Technology

Email: s.a.uspenskii@mail.ru
俄罗斯联邦, 33 ul. Sadovnicheskaya, Moscow, 117997

T. Demina

N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences

Email: s.a.uspenskii@mail.ru
俄罗斯联邦, 70 ul. Profsoyuznaya, Moscow, 117393

G. Vikhoreva

Moscow State University of Design and Technology

Email: s.a.uspenskii@mail.ru
俄罗斯联邦, 33 ul. Sadovnicheskaya, Moscow, 117997


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