Email this article A study of the viscosity of hyaluronic acid solutions for the preparation of polyelectrolyte complexes with chitosan
- Authors: Uspenskii S.A.1, Kil’deeva N.R.2, Maslova M.V.2, Demina T.S.1, Vikhoreva G.A.2
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Affiliations:
- N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
- Moscow State University of Design and Technology
- Issue: Vol 65, No 1 (2016)
- Pages: 273-276
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/237028
- DOI: https://doi.org/10.1007/s11172-016-1296-0
- ID: 237028
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Abstract
The viscosity of hyaluronic acid solutions kept at different pH values was found to decrease in the following order of pH: 6.5 > 3.5 > 4.3, although acid hydrolysis occurred at a higher rate in the most acidic solution. The poorest stability of the solutions with pH 4.3 was attributed to the compaction of the macromolecules as a result of charge density redistribution along the polyacid chains.
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About the authors
S. A. Uspenskii
N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
Author for correspondence.
Email: s.a.uspenskii@mail.ru
Russian Federation, 70 ul. Profsoyuznaya, Moscow, 117393
N. R. Kil’deeva
Moscow State University of Design and Technology
Email: s.a.uspenskii@mail.ru
Russian Federation, 33 ul. Sadovnicheskaya, Moscow, 117997
M. V. Maslova
Moscow State University of Design and Technology
Email: s.a.uspenskii@mail.ru
Russian Federation, 33 ul. Sadovnicheskaya, Moscow, 117997
T. S. Demina
N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
Email: s.a.uspenskii@mail.ru
Russian Federation, 70 ul. Profsoyuznaya, Moscow, 117393
G. A. Vikhoreva
Moscow State University of Design and Technology
Email: s.a.uspenskii@mail.ru
Russian Federation, 33 ul. Sadovnicheskaya, Moscow, 117997
