A study of the viscosity of hyaluronic acid solutions for the preparation of polyelectrolyte complexes with chitosan
- Authors: Uspenskii S.A.1, Kil’deeva N.R.2, Maslova M.V.2, Demina T.S.1, Vikhoreva G.A.2
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Affiliations:
- N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
- Moscow State University of Design and Technology
- Issue: Vol 65, No 1 (2016)
- Pages: 273-276
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/237028
- DOI: https://doi.org/10.1007/s11172-016-1296-0
- ID: 237028
Cite item
Abstract
The viscosity of hyaluronic acid solutions kept at different pH values was found to decrease in the following order of pH: 6.5 > 3.5 > 4.3, although acid hydrolysis occurred at a higher rate in the most acidic solution. The poorest stability of the solutions with pH 4.3 was attributed to the compaction of the macromolecules as a result of charge density redistribution along the polyacid chains.
Keywords
About the authors
S. A. Uspenskii
N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
Author for correspondence.
Email: s.a.uspenskii@mail.ru
Russian Federation, 70 ul. Profsoyuznaya, Moscow, 117393
N. R. Kil’deeva
Moscow State University of Design and Technology
Email: s.a.uspenskii@mail.ru
Russian Federation, 33 ul. Sadovnicheskaya, Moscow, 117997
M. V. Maslova
Moscow State University of Design and Technology
Email: s.a.uspenskii@mail.ru
Russian Federation, 33 ul. Sadovnicheskaya, Moscow, 117997
T. S. Demina
N. S. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
Email: s.a.uspenskii@mail.ru
Russian Federation, 70 ul. Profsoyuznaya, Moscow, 117393
G. A. Vikhoreva
Moscow State University of Design and Technology
Email: s.a.uspenskii@mail.ru
Russian Federation, 33 ul. Sadovnicheskaya, Moscow, 117997