Мақаланы E-mail арқылы жіберу Peptide Modulators of ASIC Channels of the Sea Anemone Urticina aff. coriacea (Cuvier, 1798) from the Sea of Okhotsk
- Авторлар: Gladkikh I.N.1, Kvetkina A.N.1, Kostina E.E.2, Kalina R.S.1, Grebnev B.B.1, Koshelev S.G.3, Kozlov S.A.3, Monastyrnaya M.M.1, Kozlovskaya E.P.1
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Мекемелер:
- Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
- Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far East Branch, Russian Academy of Sciences
- Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Шығарылым: Том 44, № 6 (2018)
- Беттер: 458-464
- Бөлім: Original Papers
- URL: https://journals.rcsi.science/1063-0740/article/view/184281
- DOI: https://doi.org/10.1134/S1063074018060044
- ID: 184281
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
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Аннотация
A search for biologically active peptides has been performed in an aqueous extract of the sea anemone Urticina aff. coriacea (Cuvier, 1798) (Actiniidae) from the Sea of Okhotsk. A separation of the peptides by size-exclusion chromatography and subsequent electrophysiological testing have shown that peptides of three fractions can completely inhibit currents of mammalian ASIC1a channels. The sea anemone Urticina aff. coriacea is believed to be a promising source of novel peptides that interact with ASIC channels.
Негізгі сөздер
Авторлар туралы
I. Gladkikh
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690022
A. Kvetkina
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690022
E. Kostina
Zhirmunsky Institute of Marine Biology, National Scientific Center of Marine Biology, Far East Branch,Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690041
R. Kalina
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690022
B. Grebnev
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690022
S. Koshelev
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Moscow, 117997
S. Kozlov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Moscow, 117997
M. Monastyrnaya
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690022
E. Kozlovskaya
Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch, Russian Academy of Sciences
Email: irinagladkikh@gmail.com
Ресей, Vladivostok, 690022
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