A Novel Method for the Rapid Determination of Isonicotinic Hydrazide in Aqueous Solutions Using Reflectance Spectrophotometry and Colorimetry
- 作者: Zrelova L.1, Belyaeva E.2, Marchenko D.2, Ivanova E.2, Sandzhieva D.2, Dedov A.2
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隶属关系:
- Sechenov First Moscow State Medical University
- Department of Chemical Technology and Ecology
- 期: 卷 73, 编号 3 (2018)
- 页面: 236-242
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182982
- DOI: https://doi.org/10.1134/S1061934818030139
- ID: 182982
如何引用文章
详细
A rapid method is developed for the quantitative determination of 5–35 g/L of isonicotinic hydrazide (INH, isoniazide) in aqueous media. The method is based on the formation of copper(I) oxide in the reaction of isonicotinic hydrazide with copper ions on the surface of indicator tablets and the subsequent recording of the analytical signal by reflectance spectrophotometry and colorimetry. Aluminum oxide is proposed as a solid-phase substrate for the production of indicator tablets. Isonicotinic hydrazide can be determined in the tablet form of the Isoniazid preparation.
作者简介
L. Zrelova
Sechenov First Moscow State Medical University
Email: dmitrismailr@mail.ru
俄罗斯联邦, Moscow, 119991
E. Belyaeva
Department of Chemical Technology and Ecology
Email: dmitrismailr@mail.ru
俄罗斯联邦, Moscow, 119991
D. Marchenko
Department of Chemical Technology and Ecology
编辑信件的主要联系方式.
Email: dmitrismailr@mail.ru
俄罗斯联邦, Moscow, 119991
E. Ivanova
Department of Chemical Technology and Ecology
Email: dmitrismailr@mail.ru
俄罗斯联邦, Moscow, 119991
D. Sandzhieva
Department of Chemical Technology and Ecology
Email: dmitrismailr@mail.ru
俄罗斯联邦, Moscow, 119991
A. Dedov
Department of Chemical Technology and Ecology
Email: dmitrismailr@mail.ru
俄罗斯联邦, Moscow, 119991
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