Silylation with the Generation of a Fixed Charge for the Analysis of Alcohols by MALDI and SALDI Mass Spectrometry
- 作者: Zhilyaev D.1, Voskresensky L.1, Polovkov N.2, Borisov R.1,2
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隶属关系:
- People’s Friendship University of Russia
- Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
- 期: 卷 73, 编号 14 (2018)
- 页面: 1323-1326
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182920
- DOI: https://doi.org/10.1134/S1061934818140149
- ID: 182920
如何引用文章
详细
A new method of the derivatization of alcohols for their analysis by matrix-assisted laser desorption/ionization (MALDI) and surface-assisted laser desorption/ionization (SALDI) is proposed. The approach is based on the silylation of the analytes with bromomethylchlorodimethylsilane in the presence of tertiary amines to yield fixed-charge containing derivatives. The proposed method was tested using aliphatic alcohols, terpenols, and sterols. MALDI and SALDI mass spectra of all derivatives contain intense ion peaks corresponding to their cationic parts.
作者简介
D. Zhilyaev
People’s Friendship University of Russia
编辑信件的主要联系方式.
Email: dimzhi@mail.ru
俄罗斯联邦, Moscow, 117198
L. Voskresensky
People’s Friendship University of Russia
Email: dimzhi@mail.ru
俄罗斯联邦, Moscow, 117198
N. Polovkov
Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Email: dimzhi@mail.ru
俄罗斯联邦, Moscow, 119991
R. Borisov
People’s Friendship University of Russia; Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Email: dimzhi@mail.ru
俄罗斯联邦, Moscow, 117198; Moscow, 119991