Development of a toolkit for early precision immunochromatographic diagnosis
- Autores: Krylsky D.1, Gushchin A.1, Gushchin S.1, Dezhurov S.1, Morenkov O.2, Gladyshev P.3, Vasiliev A.4
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Afiliações:
- Research Institute of Applied Acoustics
- Institute of Cell Biophysics
- Department of Natural Sciences and Engineering
- National Research Centre “Kurchatov Institute,”
- Edição: Volume 71, Nº 10 (2016)
- Páginas: 1063-1068
- Seção: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182130
- DOI: https://doi.org/10.1134/S1061934816100063
- ID: 182130
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Resumo
A device is developed for automated immunochromatographic assay, designed for one-time tests at the place of occurrence of a disease. The device comprises a turntable platform for up to five strips placed simultaneously, a unit for sample collection and microdosing to a test strip, a detection unit, and a microprocessor control system. A manual, semiautomatic, or automatic operation mode may be selected. Colloidal quantum dots with a luminescence peak from the visible to near-infrared spectral region (600–800 nm) are used as fluorescent labels. A UV-LED or a laser at 365–480 nm can be used as an excitation system; the detection device is a spectrometer with an operation range of 500–800 nm, based on a CCD series of TCD1304DG sensors (Toshiba). RFID tags of samples can re read and the analysis results can be sent to an external computer. The device is made in a plastic case for carrying.
Sobre autores
D. Krylsky
Research Institute of Applied Acoustics
Autor responsável pela correspondência
Email: krdvmail@mail.ru
Rússia, ul. 9 Maya 7a, Dubna, Moscow oblast, 141980
A. Gushchin
Research Institute of Applied Acoustics
Email: krdvmail@mail.ru
Rússia, ul. 9 Maya 7a, Dubna, Moscow oblast, 141980
S. Gushchin
Research Institute of Applied Acoustics
Email: krdvmail@mail.ru
Rússia, ul. 9 Maya 7a, Dubna, Moscow oblast, 141980
S. Dezhurov
Research Institute of Applied Acoustics
Email: krdvmail@mail.ru
Rússia, ul. 9 Maya 7a, Dubna, Moscow oblast, 141980
O. Morenkov
Institute of Cell Biophysics
Email: krdvmail@mail.ru
Rússia, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290
P. Gladyshev
Department of Natural Sciences and Engineering
Email: krdvmail@mail.ru
Rússia, Universitetskaya ul. 19, Dubna, Moscow oblast, 141980
A. Vasiliev
National Research Centre “Kurchatov Institute,”
Email: krdvmail@mail.ru
Rússia, pl. Akademika Kurchatova 1, Moscow, 123098
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