Determination of Tetracyclines in Milk, Eggs and Honey Using in-situ Ionic Liquid Based Dispersive Liquid–Liquid Microextraction
- Авторлар: Kaynaker M.1, Antep M.2, Merdivan M.2
-
Мекемелер:
- Graduate School of Natural and Applied Science, Tınaztepe Campus
- Chemistry Department, Tınaztepe Campus
- Шығарылым: Том 73, № 1 (2018)
- Беттер: 23-29
- Бөлім: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182947
- DOI: https://doi.org/10.1134/S1061934818010070
- ID: 182947
Дәйексөз келтіру
Аннотация
In this study, in-situ ionic liquid based dispersive liquid−liquid microextraction method for enrichment of tetracyclines before liquid chromatographic analysis has been improved. A 1-benzyl-3- methylimidazolium chloride was used as an ionic liquid. To increase extraction efficiency, some optimization parameters (amount of ammonium hexafluorophoshate, extraction time, centrifugation time, ratio of ionic liquid/salt) were investigated. At optimized conditions, enrichment factors of four tetracycline antibiotics (tetracycline, chlortetracycline, methacycline, doxycycline) were between 25 and 98. The residues of tetracyclines were not found in the studied real samples. For the accuracy of the method, the concentration of 50 and 250 μg/L of standard tetracycline mixture solutions were spiked to the blank real milk, honey and egg samples and the percentage recoveries were obtained in the range of 75.8–109.7%.
Авторлар туралы
Melis Kaynaker
Graduate School of Natural and Applied Science, Tınaztepe Campus
Email: melek.merdivan@deu.edu.tr
Түркия, Izmir, 35160
Mine Antep
Chemistry Department, Tınaztepe Campus
Email: melek.merdivan@deu.edu.tr
Түркия, Izmir, 35390
Melek Merdivan
Chemistry Department, Tınaztepe Campus
Хат алмасуға жауапты Автор.
Email: melek.merdivan@deu.edu.tr
Түркия, Izmir, 35390