Determination of Tetracyclines in Milk, Eggs and Honey Using in-situ Ionic Liquid Based Dispersive Liquid–Liquid Microextraction
- 作者: Kaynaker M.1, Antep M.2, Merdivan M.2
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隶属关系:
- Graduate School of Natural and Applied Science, Tınaztepe Campus
- Chemistry Department, Tınaztepe Campus
- 期: 卷 73, 编号 1 (2018)
- 页面: 23-29
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182947
- DOI: https://doi.org/10.1134/S1061934818010070
- ID: 182947
如何引用文章
详细
In this study, in-situ ionic liquid based dispersive liquid−liquid microextraction method for enrichment of tetracyclines before liquid chromatographic analysis has been improved. A 1-benzyl-3- methylimidazolium chloride was used as an ionic liquid. To increase extraction efficiency, some optimization parameters (amount of ammonium hexafluorophoshate, extraction time, centrifugation time, ratio of ionic liquid/salt) were investigated. At optimized conditions, enrichment factors of four tetracycline antibiotics (tetracycline, chlortetracycline, methacycline, doxycycline) were between 25 and 98. The residues of tetracyclines were not found in the studied real samples. For the accuracy of the method, the concentration of 50 and 250 μg/L of standard tetracycline mixture solutions were spiked to the blank real milk, honey and egg samples and the percentage recoveries were obtained in the range of 75.8–109.7%.
作者简介
Melis Kaynaker
Graduate School of Natural and Applied Science, Tınaztepe Campus
Email: melek.merdivan@deu.edu.tr
土耳其, Izmir, 35160
Mine Antep
Chemistry Department, Tınaztepe Campus
Email: melek.merdivan@deu.edu.tr
土耳其, Izmir, 35390
Melek Merdivan
Chemistry Department, Tınaztepe Campus
编辑信件的主要联系方式.
Email: melek.merdivan@deu.edu.tr
土耳其, Izmir, 35390
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